The Associate Scientist I/II will be part of a translational biomarker unit, part of the Cell Biology and Immunology group, focused on characterizing novel antibody-based therapies for the treatment of cancer. In this position the employee will be responsible for evaluating biological responses to candidate therapeutic molecules in a range of phenotypic analyses and immune cell-based assays.

Responsibilities and Job Duties:

• Isolation of human primary cell subtypes from normal or diseases human sources, including blood or tissues (peripheral blood mononuclear cells, T cell subpopulations, myeloid cells, B cells, etc)
• Perform flow cytometry analysis phenotypic and functional analyses to investigate the clinical candidate molecules' binding properties, induced phenotype changes, and biological responses in different cell subsets
• Develop new methods and technologies for implementation and project advancement under minimal supervision
• Collect, analyze, and reports results to supervisor under minimal supervision
• Maintain detailed records of experimental data and protocols
• Work with the Director/Associate Director to prepare data summary and data reports
• Assist lab members by performing research laboratory work following established protocols
• Maintain instrument and lab equipment
• Maintain inventory and help with ordering stock laboratory supplies and reagents
• Maintain a safe and clean laboratory environment

Minimum Qualifications

Associate Scientist II, Translational Biomarker Group

Education & Credentials

• Bachelor's Degree in scientific discipline with a minimum of eight (8) years of related experience

OR

• Master's Degree in a scientific discipline with a minimum of five (5) years of related experience

Associate Scientist I, Translational Biomarker Group

Education & Credentials

• Bachelor's Degree in scientific discipline with a minimum of five (5) years of related experience

OR

• Master's Degree in a scientific discipline with a minimum of two (2) years of related experience

Knowledge, Skills and Abilities

• General mammalian tissue culture
• Proven working knowledge of basic cell biology and molecular techniques including ELISA assays
• Proficiency in basic immunology techniques and flow cytometry
• Ability to work independently, be able to problem solve and know when to ask for assistance
• Ability to multitask
• Ability to communicate results effectively both written and orally
• Proven capability in data analysis, use of analytical toos (e.g., spreadsheets, ststistical software) and data presentation
• Demonstrated ability to collaborate with other members of a team
• Strong computer skills, including proficiency with basic data analysis programs (Microsoft Office, Graphpad Prism, etc.)

Supervisory Responsibilities

None

Preferred Qualification:

• Basic knowledge of mass cytometry and spectral cytometry is preferred.

Statement

MacroGenics is proud to be an equal opportunity employer. Employment selection and related decisions are made without regard to race, color, national origin, sex, gender identity, sexual orientation, religion, age, disability, protected veteran status, or any other characteristic protected by federal, state or local law. We are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the employment process, please email info@macrogenics.com or call (301) 354-3566 and/or 711 for TTD/TTY service.

Equal Opportunity Employer/Veterans/Disabled

We do not accept non-solicited resumes or candidate submittals from search/recruiting agencies.