Job Description

Associate Director, Raw Materials Planning

Job Posting Description

Vertex has established a new research site in the Boston area where research, development, and clinical manufacturing for cell and genetic therapies is primarily based. Cell and genetic therapies represent two rapidly emerging therapeutic modalities with the potential to treat-and even cure-several of the diseases Vertex is focused on, including sickle cell disease, Duchenne muscular dystrophy and type 1 diabetes. Further investment in a research site specifically designed to advance these programs will be key to Vertex's continued and sustained leadership in these exciting approaches. At Vertex Cell and Genetic Therapies (VCGT) our research teams will bring together the best biology, technologies and enhanced manufacturing capabilities to ensure we bring these cutting-edge transformative therapies to patients as quickly as possible.

Vertex is seeking an Associate Director, Raw Material Planning to lead raw material planning for all direct and indirect materials and manufacturing sites, supporting all VCGT programs. This position will support Vertex's cell and gene programs.

The Associate Director, Raw Materials Planning will join the fast-growing supply chain team and report to the Director of VCGT Materials Operations. The position will support multiple process development and clinical manufacturing sites located in Providence, RI, Cambridge, MA, and Boston, MA.

This is a Hybrid eligible position that requires 3 days per week on site. You may also elect to be onsite 5 days a week w ad hoc flexibility.

Responsibilities:

• Leads team development and harmonization by utilizing exceptional leadership and team building skills. Leads creation of team goals and works by example, fostering collaboration across team.
• Collaborates closely with Finance to communicate anticipated budget changes and projections. Provide quarterly projections to Leadership to ensure alignment on anticipated risks and adjustments.
• Contributes to overall strategic development of a supply planning function including working with other cross functional leaders to integrate the activities of the function. Presents overall group strategy and high-level material operations issues
• Proactively drives resolution across various cross-functional groups (such as Quality, Tech Ops, Regulatory, Process Development, etc.) to resolve issues that may block the timely flow of materials or projects. Prioritize and track high risk materials and their potential impact to our business and production operation. Collaborate with internal stakeholders in the development and execution of product strategies. Communicate progress to management and key stake holders on material plan changes
• Analyze demand forecasts, production schedules, and inventory levels to optimize materials planning processes. Work closely with Capacity and Patient Demand Planning team to incorporate S&OP process and data into raw material plans. Assist in the enhancement, execution, and management of the raw material risk management strategy and process that addresses any potential disruption to each of the programs within VCGT. Identify and mitigate risks related to supply chain disruption and delays, supplier product and / or manufacturing changes and supplier inability to support current or future demands
• Analyze raw material consumption across cell and device manufacturing demands . Identify areas of risk and cost savings opportunities. Collaborate with key stakeholders to help solve supplier and material related issues (backorders, product quality concerns).
• Partner with Research and Development teams and support new product introduction by proactively partnering with other materials operations functions.
• Partner with Strategic Sourcing, Procurement, and CMC to ensure the supplier and material selection process is aligned with the overall product strategy. Partner with other functions to drive introduction of clinical grade materials and other projects to prepare for late-phase manufacturing.
• Support Materials Management and the E&O process by ensuring the integrity of MRP, KANBAN and maintaining appropriate inventory levels of raw materials.
• Utilize business systems (Oracle ERP, OBI, ect) to manage and interpret material data. Research past and expected spend levels to understand and action areas of cost savings opportunities and potential risk.
• Maintain strong cross functional relationships to bolster communication with internal and external stakeholders

Required Qualifications:

• Bachelor's Degree in Supply Chain/Manufacturing/Science/Business Operations related disciplines
• 8+ year of Biotech, Pharmaceutical or CRO company related work experience
• Proven ability to manage multiple projects with high degree of effectiveness
• Possesses a distinguished record of delivering on critical project goals and moving projects forward
• Exhibits robust knowledge across supply chain disciplines
• Knowledge in overall drug development
• Demonstrates strong aptitude for managing and motivating others and building team unity
• Proven ability to communicate clearly and concisely (written/oral) with all levels of the company
• Good understanding of the medical device and biotech industry and market
• High level understanding of GMP processes and regulatory requirements; experience in GMP environment.
• Ability to effectively plan, prioritize, execute, follow up and anticipate challenges
• Results orientated with strong sense of urgency to mitigate risk and close issues *
• Knowledge of ERP setups with skills and proficiency to include MRP and ability to download and analyze data
• Experience with quality management systems (change controls, deviations, etc)
• Ability to communicate complex problems and necessary decision points both visually and verbally
• Excellent interpersonal, verbal, and written communication skills

#LI-hybrid #LI-SV1

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